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Will Bioidentical Hormone Replacement Therapy (BHRT) Help My Mood Swings?

by Medical Review Board

Bioidentical hormone replacement therapy (BHRT) is a treatment approach that uses chemically identical hormones like those produced naturally in the body to address hormone imbalances. While BHRT may be effective in managing specific symptoms related to hormonal fluctuations, it’s essential to understand its potential benefits and limitations regarding mood swings, anxiety, and depression. 

Mood Swings

Mood swings can be associated with hormonal changes, particularly in women during their menstrual cycle, perimenopause, and menopause. BHRT may help stabilize hormonal fluctuations and improve mood swings in some individuals. However, the effectiveness can vary from person to person. It may not be the sole solution for managing mood swings. Lifestyle changes, stress management, and therapy can also play important roles.


Hormonal imbalances, such as those occurring during menopause or in conditions like polycystic ovary syndrome (PCOS), may contribute to anxiety symptoms in some individuals. BHRT can potentially help alleviate anxiety related to hormonal issues, but the underlying causes of anxiety can influence its effectiveness. It’s essential to consult with a healthcare provider to determine if BHRT is appropriate and safe for addressing anxiety. 


Depression is a complex mental health condition with various causes, including genetic, environmental, and biochemical factors. Hormonal imbalances can contribute to mood changes and exacerbate depressive symptoms in some cases (e.g., postpartum depression or premenstrual dysphoric disorder). BHRT is not typically a first-line treatment for depression. Antidepressant medications, psychotherapy, and lifestyle modifications are often more commonly recommended for managing depression.

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Before considering BHRT for mood swings, anxiety, or depression, it’s important to take the following steps: 

Consult a Healthcare Provider

Speak with a qualified healthcare provider, such as a BodyLogicMD practitioner. BodyLogicMD practitioners are hormone experts. We can assess your hormonal status and overall health to determine if BHRT is appropriate for your specific situation. 

Consider Other Treatment

Discuss alternative treatments and interventions for mood swings, anxiety, and depression with your healthcare provider. These may include counseling, cognitive-behavioral therapy, lifestyle changes (e.g., exercise, diet, stress management), and medication when necessary. 

Learn About Bioidentical Hormone Replacement Therapy (BHRT) for Women

Regular Monitoring

If you and your healthcare provider decide that BHRT is an appropriate treatment, it should be closely monitored to ensure that it’s effective and safe for you. Adjustments may be needed over time.


In conclusion, BHRT may help with mood swings, anxiety, or depression when these symptoms are related to hormonal imbalances, but it’s not a one-size-fits-all solution. Individualized treatment plans, consultation with a BodyLogicMD practitioner, and consideration of other treatment options are essential steps in addressing these mental health concerns effectively.