Bioidentical Hormone Replacement Therapy (BHRT) has gained significant attention as a natural alternative to traditional hormone replacement therapies. Many individuals seek BHRT to alleviate symptoms of hormonal imbalances caused by aging, menopause, and other health conditions. But what exactly is BHRT made from? Understanding the sources and composition of these hormones can help patients make informed decisions about their treatment.
We will review the origins, extraction processes, and composition of bioidentical hormones and how they compare to synthetic hormones.
What Are Bioidentical Hormones?
Bioidentical hormones are compounds with the same molecular structure as the hormones naturally produced by the human body. This structural similarity allows them to be effectively utilized by the body without causing the adverse effects associated with some synthetic hormones.
The primary bioidentical hormones used in BHRT include:
- Estrogens (Estradiol, Estriol, Estrone)
- Progesterone
- Testosterone
- DHEA (Dehydroepiandrosterone)
- Pregnenolone
Natural Sources of Bioidentical Hormones
Unlike synthetic hormones, which are typically derived from animal sources or chemically synthesized in a lab, bioidentical hormones are derived from natural plant sources. The most common sources include:
Soybeans
Soy contains phytoestrogens, plant-based compounds that mimic estrogenic activity in the body. The key component derived from soy is diosgenin, which serves as a precursor for synthesizing bioidentical estrogens and progesterone.
Wild Yams (Dioscorea Villosa)
Wild yams are another major source of diosgenin, which can be converted into progesterone, estrogen, and other steroid hormones in a laboratory setting. However, the body cannot directly convert wild yam extracts into usable hormones; they must undergo chemical transformation in a compounding pharmacy.
The Process of Extracting Bioidentical Hormones
The process of creating bioidentical hormones involves several steps:
- Extraction: Diosgenin is extracted from soybeans or wild yams.
- Conversion: The extracted diosgenin undergoes a series of chemical reactions in a lab to transform it into bioidentical hormones.
- Purification: The hormones are purified and tested to ensure they are structurally identical to human hormones.
- Formulation: The final bioidentical hormones are compounded into various delivery methods, such as creams, gels, capsules, injections, or sublingual tablets.
How Bioidentical Hormones Differ from Synthetic Hormones
Traditional hormone replacement therapy (HRT) often uses synthetic hormones, which can have different molecular structures from the hormones naturally produced by the body. For example:
- Synthetic estrogen: Derived from pregnant mare’s urine (Premarin) or chemically synthesized.
- Synthetic progesterone (Progestins): Chemically altered to have a longer half-life but may cause side effects such as bloating, mood swings, and increased risk of blood clots.
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Because bioidentical hormones match human hormones structurally, they are believed to have fewer side effects and better efficacy in restoring hormonal balance.
Forms of Identical Hormones and Their Uses
Bioidentical hormones can be customized to meet individual needs and are available in various forms:
- Creams and gels: Absorbed through the skin, offering a steady release of hormones.
- Patches: Provide continuous hormone release through transdermal absorption.
- Capsules and tablets: Offer a convenient oral method but may undergo metabolism in the liver.
- Injections: Used for immediate and sustained release in the bloodstream.
- Pellets: Implanted under the skin for long-term hormone delivery.
Are Bioidentical Hormones Safe?
One key advantage of BHRT is that it can be customized to match an individual patient’s hormonal profile. While some research suggests that bioidentical hormones may carry fewer risks than synthetic alternatives, all hormone therapies should be used under medical supervision. Factors such as dosage, method of administration, and individual health conditions must be considered to ensure safety and effectiveness.
BHRT is made from plant-derived compounds, primarily from soybeans and wild yams. These sources provide diosgenin, which is converted into bioidentical hormones through laboratory processes. Unlike synthetic hormones, bioidentical hormones have an identical molecular structure to human hormones, potentially offering better compatibility and fewer side effects.
If you’re considering BHRT, consult a knowledgeable BodyLogicMD practitioner to determine the best approach for your unique needs. Understanding what goes into your therapy is the first step toward achieving optimal hormonal balance and overall well-being.
About BodyLogicMD
BodyLogicMD is a leading network of wellness centers specializing in personalized treatments to help clients achieve optimal health and vitality. With a focus on bioidentical hormone replacement therapy (BHRT), weight loss solutions, and integrative medicine, BodyLogicMD works with patients to create individualized plans that address unique health needs. The BodyLogicMD team of experts is dedicated to empowering individuals to feel youthful, energized, and balanced, all while providing compassionate, customized care.
